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BHB serves as ancillary fuel substituting (but also inducing) anti-oxidative, anti-inflammatory, and cardio-protective features by binding to several target proteins, including histone acylation modification, or G protein-coupled receptors (GPCRs)

Lang CA, Mills BJ, Lang HL, Liu MC, Usui WM, Richie J, et al. High blood glutathione levels accompany excellent physical and mental health in women ages 60 to 103 years. Journal of Laboratory and Clinical Medicine. 2002;140: 413417. doi:10.1067/mlc.2002.129504

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by itching, epidermal barrier dysfunction, and an unbalanced inflammatory reaction