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In an effort to determine whether the tumor-targeting IL-4R-aptamer liposomecytosine-phosphate-guanine oligodeoxynucleotides (CpG ODN) delivery system could deliver CpG into tumors and circumvent immunosuppressive TME [71], Liu et al
The brain regions in which these genes are expressed include the amygdala, subgenual anterior cingulate, and dorsolateral prefrontal cortex, and the associated molecular pathways include reduced neurotrophic support, neural signaling, and GABA function
Tertiary adrenal insufficiency caused by exogenous steroid medication is common but difficult to diagnose due to its non-specific symptoms (21)
thus, mitochondrial ROS are required for ferroptosis 29
