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STIM2 is thought to have a lower affinity for Ca 2+ since STIM1-deficient mouse T cells and fibroblasts bear a severe impairment in store-operated Ca 2+ influx whereas a deficiency in STIM2 has a less dramatic effect (72)

Not a peptide CHEMICAL STRUCTURE Molecular Formula : C 10 H 11 N 2 + Source: PubChem Mechanism of Action 5-Amino-1MQ acts as a highly selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), blocking the methylation of nicotinamide (a form of vitamin B3) using S-adenosyl methionine (SAM) as a methyl donor

doi: 10.1007/s13139-017-0475-8 5 AlievaA

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