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We measured oxidative stress levels through malondialdehyde (MDA), a naturally occurring product of lipid peroxidation, and an established marker for oxidative stress

separation was carried out using a non-isocratic method, starting at 23% ACN and climbing to 31 % ACN over 9 minutes, at ambient temperature and a flow rate of 0.3 mL/min

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Hydrogen bonds, however, are distinct from dipoledipole interactions for two main reasons: (1) fluorine, oxygen, and nitrogen are highly electronegative, so the partial charges involved are large, and (2) the hydrogen atom is very small, which allows the partial positive charge on hydrogen to be very close to the partial negative charge on the H-bond acceptor

The presence of gyri can significantly affect the movement of the brain within the skull, and lead to more brain deformation (Finnie, 2001