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This can reduce the risk of chronic diseases associated with oxidative stress, such as heart disease and cancer

Similarly, HFD-induced obesity with BMAT expansion reduces long-term Lin Sca1 + c-Kit + (LSK) stem cells and shifts cell differentiation from a lymphoid to myeloid lineage, leading to poor reconstitution of HSCs (316)

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Tailoring interventions to diverse cultural and socioeconomic backgrounds will also be important, as perceptions of fatigue and access to resources can vary widely
