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In the first case, the alkylation of the imide nitrogen of the glutarimide ring is carried out only after the condensation of the glutarimide and phthalimide moieties, under conditions similar to those of the pre-conjugation alkylation (compounds 135 or 136 ) 190

doi: 10.1007/s10620-019-05844-8
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[DOI] [PMC free article] [PubMed] [Google Scholar] Lepetsos P

The supernatant was mixed with 1 ml ice-cold 10% ethanol and 50 l 3 M sodium acetate pH 5.2
