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Similarly, this compound inhibits Th17 and Th1 cell differentiation by reducing STAT3 and STAT4 phosphorylation, respectively, and suppresses mTORC1 pathway activity independently of PI3K/AKT and ERK signaling in DSS-induced colitis mice [495]
[DOI] [PubMed] [Google Scholar] 374.Giugliano T., Santoro C., Torella A., Blanco F.D.V., Grandone A., Onore M.E., Melone M., Straccia G., Melis D., Piccolo V., et al
Colchicine has been a medicine widely used in GA for a long history
(2019) (Kohn et al
10.1002/biof.1476 Biofactors
