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If your deficit is mild, you may respond quickly to medication and eating more foods containing B12

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Methylisocitrate lyase (MCL, PrpB) converts methylisocitrate to pyruvate and succinate (EC 4.1.3.30) in a reaction analogous to that catalyzed by isocitrate lyase (ICL) in the glyoxylate shunt

A deficiency can also cause issues such as diarrhea, nausea, vomiting, lack of appetite, weight loss, pale skin, numbness and tingling in your hands and feet, confusion, irritability, depression, and behavior changes

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