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doi: 10.1074/jbc.M111451200 186 WangYGLongJShaoDCSongH

Gambini D, Ferrero S, Kuhn E

Pathological angiogenesis facilitates tumor cell dissemination and metastasis

IGF-1, as a nutrient-responsive growth factor, activates NF-B and the expression of downstream genes (Ccdn1, Vegf, Birc5 and Ptgs2) to promote the growth of pancreatic cancer in vitro and in vivo (88)