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Description
These molecular defects converge on distinct stress programs in individual organelles, impairing proteostasis, vesicular trafficking, metabolic function or degradative capacity

An example of this is the situation that occurs in HIV/AIDS patients who experience a persistent drop in tissue glutathione (GSH) levels

the complex could be cleaved with hydroxylamine, which hydrolyzes primarily ester bonds, and liberated IgG exclusively bound to separated band 3, indicating that autologous anti-band 3 IgG specifically reacted to the aggregated band 3-complement complexes

Integrated network pharmacology approach for drug combination discovery: a multi-cancer case study

Gomez-Lechon, M
