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Norata GD, Callegari E, Marchesi M, Chiesa G, Eriksson P, Catapano AL

Reperfusion leads to an overload of ROS and inflammatory cytokines, as well as RGC apoptosis

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Nat Rev Immunol (2017) 17:54558

The glutathione system consisting of glutathione reductase, glutathione oxidase and glutathione, maintains the concentration of O 2 and H 2 O 2 at physiological levels necessary for tissue repair and immune defence [3]