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Description
Given the important central role of this cofactor and its relevance to mitochondrial function, this review will provide an extensive summary of the NAD + homeostasis and modulation approaches, of the various mechanisms of NAD + -mediated mitochondrial regulation, and how the functional link between NAD + and mitochondria has been investigated in the context of preclinical and clinical settings of aging and disease
Self-prescribing B12 injections for weight loss purposes is not supported by clinical evidence and may delay diagnosis of underlying conditions contributing to weight concerns or low energy levels
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PMCID: PMC4434546
Songtao Zhao, MD3,6
