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Cotransfection of the human ABCA1 promoter and an expression vector for TR resulted in suppression of the ABCA1 promoter in the presence of T 3 (122)
333,334 It is defined by recurring episodes of inflammatory arthritis affecting joints and specific soft tissues, including cartilage, synovial bursae, and tendons, particularly in the lower extremities, due to the deposition of uric acid in the form of monosodium urate crystals

They also perused the reference lists of all eligible studies and relevant reviews