glutathione s-conjugate The role of glutathione-S-transferase in anti-cancer drug resistance 16 Phase II reactions Conjugation

Description

Metabolic activation of specific natural products from herbal and dietary supplements is mediated by hepatic cytochrome P450 or intestinal bacteria, and generates chemical reactive/toxic metabolites that bind to cellular reduced glutathione or macromolecules, and form reactive metabolites-glutathione/protein/DNA adducts, and these protein/DNA adducts can result in toxicities

But then, as a junior professor, there are boundaries between you and the people you work with, and those are important boundaries

[DOI] [PMC free article] [PubMed] [Google Scholar] [24].Alam J, Camhi S, Choi AMK

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