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doi: 10.1002/glia.1106

This scaffold system has also been shown to induce MenSC differentiation into keratinocyte-like cells (Mirzadegan et al., 2022), while upregulating VEGFA to activate CD34 + endothelial cells and stimulate angiogenesis

The most relevant research areas include muscle metabolism, bone metabolism, glucose homeostasis, tissue regeneration, glucocorticoid response, cardiovascular function, neuroendocrine tissues, and experimental models evaluating the relationship between GH, IGF-1, ghrelin, and energy regulation

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These differences likely reflect not only hormonal influences, but also sex-specific patterns of fat distribution, substrate utilization, and adaptive thermogenesis