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The essential protocol is described below

Under normoxic conditions, Nrf2 binds to Keap1 and continues to be inactivated by ubiquitination and degradation in the proteasome (Lu et al., 2017)

Administration of the mGlu 2/3 -selective agonist LY379268 also blocks the acquisition and expression of behavioral sensitization to amphetamine (Kim and Vezina, 2002

24 h) inhibits Wnt/-catenin signaling in CLL cells [1]
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