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[00038] "Amino acid" as used herein refers to the biologically important organic compounds made from amine (-NH 2 ) and carboxylic acid (-COOH) functional groups, [00039] "Carboxylic acids" as used herein refers to organic acids characterized by the presence of one or more carboxyl groups in their molecules that consists of a carbon atom attached to an oxygen atom with a double covalent bond and to a hydroxyl group by a single covalent bond

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The 'H-NMR proves that there is no signal corresponding to the carboxylic acid (COOH) around 12-13 ppm (Fig

For example, irradiation (250 W lamp) of an oxygen-purged solution of LA in methanol containing 0.05% methylene blue at 5 C produces a mixture of 9( R,S )- and 13( R,S )-HpODEs as well as 10( R,S )-HpODE 3 and 12( R,S )-HpODE 4 (Scheme 54)

Accordingly, inventors of the present invention have provided various embodiments showing at least 30 %, at least 50 %, at least 70 % and at least 90 % release over 24 hrs when tested in an In Vitro study using a Franz Diffusion Cell employing a dialysis membrane with l2-l4kd molecular weight cut off