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Studies have shown that agonists of muscarinic ACh receptors, including ACh, can alleviate the symptoms of cardiac arrhythmia without affecting the contractility of the heart (66)

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[37] Fruits and vegetables are the major sources of carotenoids in the human diet

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Studies suggest that the uniqueness of their mechanisms might provide an opportunity to probe downstream signaling implications such as ERK1/2 activation, cAMP modulation, and calcium channel involvement, although much of this remains theoretical and dependent on research design