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Activation of TLR3 receptors in microglia causes increased release of IL-1 and TNF-, which increases SERT expression in astrocytes and, therefore, 5-HT reuptake and its degradation to the metabolite 5-HIAA, thus reducing extracellular 5-HT levels

Blood pressure and waist size were also lowered

[Google Scholar] 230.Bahrya H., Abdalla R., Pons A., Taha S., Vial C

Effect of IMiD compounds on CD38 expression on multiple myeloma cells: MOR202, a human CD38 antibody in combination with pomalidomide