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This makes injections an effective and straightforward way to ensure the body receives the right amount of B vitamins to function properly

Prospective randomized controlled studies of oral vitamin B12 treatment in patients with vitamin B12 deficiency, including patients with Biermers disease [21,22] Table 3

Without intrinsic factor, people develop vitamin B12 deficiency, with symptoms such as fatigue, a distinctive change in red blood cells, nausea, indigestion and other digestive problems, weakness, headaches and weight loss

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However, some people may have difficulty absorbing B12 from their diet, particularly if they have gastrointestinal disorders or have had gastrointestinal surgery