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Intracellular signaling by the unfolded protein response

Keep them available for occasional use, but try days without

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This regulation and inactivation is important because hyperactive ERO1 is a source of oxidative damage ( While ERO1 has been suggested to be the major regulator of PDI redox cycling, it is not required for disulfide formation in mammals, which prompted identification of other redox regulators in the ER

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Jordan V