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Since silymarin's therapeutic concentration is substantially lower than that of silibinin, silymarin is unlikely to cause hepatic medication interactions when taken as prescribed (Bijak, 2017)
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(79) showed that promoting CB proliferation and SCFA production repairs the colonic mucosal barrier in DSS-induced mice by upregulating tight-junction proteins and increasing goblet cell numbers, dependent on CB -mediated amino acid and 2-oxocarboxylic acid metabolism

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