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As with any innovative therapy, we emphasize a cautious, evidence-informed approach
For example, the genes encoding transferrin receptor (TFRC), glucose transporters and the master antioxidant regulator NRF2 are closely associated with the pathological progression of AD (49)
As iron accumulation favors ROS generation and ferroptosis, it is plausible that the high iron exposure in the intestine is related to the tissues increased sensitivity to IR
doi: 10.1038/s41423-020-00630-3 40 KhouryMKGuptaKFrancoSRLiuB
2015;52, Part B:344362
