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The samples were centrifuged at 8000 g and 4 C for 10 min, and the organic layer was collected into a new tube and stored at 80 C until electron spin resonance (ESR) measurement 7

miRNA sequences were downloaded from RNAcentral database ( tRNA sequences were obtained from GtRNAdb ( using High confidence GRCH38/hg38 tRNA sequences, lncRNA were downloaded from LNCipedia (PMCID: PMC3531107) and rRNA reference sequence was built using U13369.1, NR_145819.1, NR_146144.1, NR_146151.1, NR_146117.1, X12811.1, NR_003287.4, NR_023379.1, NR_003285.3 and NR_003286.4

These mechanotransduction machines impose regulatory constraints at the level of cell-cell and tissue-tissue networks but some cells are better at mechanotransduction than others, and therefore more sensitive to mechanical forces and dysregulated in disease

In the presence of ferrous iron (Fe 2+ ), cysteinyl-glycine - a product of GGT actioninitiates a series of reactions leading to the generation of reactive oxygen species and increased oxidative stress