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indicates that while the tests sensitivity is about 70% when compared to nerve conduction studies (NCS) and autonomic function testing (AFT), its specificity and negative predictive value are extremely low0% against AFT and 20% against NCS

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Some studies suggest that VEGF promotes neuroprotection by signaling through the neuropilin receptor expressed in DA neurons, and indirectly by activating the proliferation of astroglia and by promoting angiogenesis [32,131,132]

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