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these findings are summarized in Table 3 and schematically represented in Figure 3

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doi: 10.1016/j.neulet.2015.07.005 57

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Definition of osteoarthritis Osteoarthritis has been defined as a chronic disorder characterised by:3 focal erosive lesions cartilage destruction subchondral sclerosis cyst formation large osteophytes at the margins of the joint

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Complex IV (cytochrome c to oxygen): The final step releases approximately -23 kcal/mol , as electrons combine with oxygen and protons to form water

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