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Baar et al., FOXO4-DRI reduced the lifespan of primary human fibroblasts IMR90 induced into senescence by ionizing radiation by over 11 times (11.73 times), compared to the control group consisting of non-senescent IMR90 cells [127]
Being able to return to previously limited activities often matters more than achieving a completely pain-free state
10.1210/er.2009-0026 54 HuangQ.ChenH.YinD.WangJ.WangS.YangF.et al (2024)
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A predictive model for selective targeting of the Warburg effect through GAPDH inhibition with a natural product
