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Nevertheless, the prognosis is not promising either, as few people live to adulthood [8184]

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Besides, bromelain radiosensitizing action could be expressed through increasing lipid peroxidation and ROS production in tumor tissue, inhibition of repair of DNA strand breaks and inhibition of proliferation (153)

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By secreting capsular components that stimulate microglia to produce IL-8, a potent neutrophil chemoattractant, cryptococcal cells paradoxically impair neutrophil recruitment