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doi: 10.1016/j.celrep.2019.07.002

(Curr Pharm Des, 2018) estableci que las propiedades gastroprotectoras del BPC-157 funcionan a travs de mecanismos tanto sistmicos como locales, pero lograr niveles teraputicos en sangre requiere consideracin cuidadosa del mtodo de suministro

Rearrangement of LBD-TMD linkers and pore expansion The LBD layer rearrangements described above raise the question of how these conformational changes may be transmitted to the pore domain

W.et al (2004)

5 DMF is taken orally and, following ingestion, is converted by gut esterases to monomethylfumarate (MMF), which is hydrolysed to fumaric acid and metabolised via the citric acid cycle