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This may be due to the triggering of various bypass signaling pathways and the diversity of tumors [30,31,32]

Continue increasing by 2.5mg every four weeks as tolerated, up to a maximum of 15mg weekly

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When To Contact Your Clinician Without Delay It requires immediate contact with your physician if you experience: Severe or persistent abdominal pain Persistent vomiting or diarrhea causing dehydration Fever with severe abdominal pain Signs of low blood sugar that you cannot manage Sudden bile duct type symptoms Allergic reactions at the injection site or system-wide Realistic Expectations Without Promises Link Individual response varies, and long-term safety beyond trial periods needs more data