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[DOI] [PMC free article] [PubMed] [Google Scholar] Aschner M, Yao CP, Allen JW, Tan KH

& Blutt, S

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Transitioning from these cellular findings to the robust identification of these circulating oxidized byproducts (such as 4-HNE, specific epoxy-derivatives, or altered ceramide ratios) in the bloodstream will solve two problems at once: providing a reliable, non-invasive tool to monitor FRDA progression and offering definitive proof of target engagement when testing new anti-ferroptotic drugs

International journal of oncology, 48(2), 836842