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Description
In vivo sepsis model Sepsis was induced in C57BL/6J mice by intraperitoneal (IP) injection with LPS (10 mg/kg) for 2 hr followed by 100 mM/100l, pH 7.4 ATP (Sigma-Aldrich, A7699) IP injection as previously described (53)
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The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy
It can impair the function of white blood cells and other immune issues
