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The Retatrutide downregulated key profibrotic mediators, including Col1a1 , Spp1 , and Tgfb1 , while upregulating angiogenic ( Vegfa ) and anti-fibrotic ( Bmp4 , Bmp6 ) genes
Journal of Pharmacology and Experimental Therapeutics 308: 1138-1147.CrossRefGoogle ScholarPubMed HOPPEL, C
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Although the transcription factors SBP-1/SREBP 31,32 and DAF-16/FOXO 49 are master regulators of lipogenesis, these proteins do not respond to nucleolar stress (Supplementary Fig
