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Moreover, an increase in IL-1, TNF-, IFN-, expressions of inducible nitric oxide synthase (iNOS), levels of monocyte chemoattractant protein-1, NF-B/p65, and activity of adenosine deaminase, showing inflammation, and altering arginase activity, and collagen-1 levels in renal tissues

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[3] Controlled evidence demonstrating clinically meaningful weight loss from these injections is lacking