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Evidence is emerging that both pro-inflammatory cytokines and oxidative stress play a key role in OL cell pathology in MS

Multiple studies (in vitro and in vivo) demonstrate the association between IGF-1 deficit and deregulated lipid metabolism, cardiovascular disease, diabetes, and an altered metabolic profile of diabetic patients

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IGF-I/IGF-binding protein-3 combination improves insulin resistance by GH-dependent and independent mechanisms

For example, Sara, a marathon runner, used IV therapy after a big race