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Network pharmacology has predicted 96 potential molecular targets and relevant signaling pathways, with KEGG analysis highlighting Bcl-2, BAD, JNK, p38, and ERK1/2 as key nodes
Apart from diurnal rhythms, plasma cortisol levels increase towards the end of pregnancy, and this is further accelerated during delivery 16
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All the simulations were performed with the CHARMM36m force field and GROMACS software 67,68
