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In a controlled trial, 604 cognitively unimpaired people (6584 years of age) with overweight or obesity and a history of familial Alzheimer disease were randomized to a control diet (mild calorie restriction only) or MIND diet plus mild calorie restriction for three years

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Researchers consistently identify properly designed human clinical trials as the critical next step for establishing clinical relevance

In this review, we introduce the various biosynthetic and bioenergetic roles of glutamine based on the compartmentalization of glutamine metabolism to explain why cells exhibit metabolic reliance on glutamine

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