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Uncontrolled high blood sugar induces oxidative stress, which is accompanied by an increase in inflammatory cytokines (proteins) and advanced glycation end products (glycotoxins)

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By comparing the samples from the I/R and I/R + M groups, it can be concluded that the prevalence and intensity of liver regeneration is significantly higher in the animals pre-treated with meldonium 68 , proved with the lower Suzuki histological score in samples from the I/R + M group in comparison to samples from the I/R group (Table 6)

Greensboro Sawyer, Kenneth R