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10.1111/pcmr.12404 149 LeeH

Pediatr Res 96(3):632642 Ali I, Adil M, Imran M, Qureshi SA, Qureshi S, Hasan N, Ahmad FJ (2025) Nanotechnology in Parkinsons disease: overcoming drug delivery challenges and enhancing therapeutic outcomes

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Notably, the researchers reported an eightfold improvement in survival and a 16-fold improvement in dopaminergic differentiation, suggesting that supportive hydrogels could significantly enhance the effectiveness of iPSC-derived cell therapy for PD

Moreover, diverse extracellular molecular signals, including neurotransmitters, neurotrophins, extracellular matrix proteins, contact-mediated ligands, and secreted diffusible cues, shape neural circuit development and modulate brain connectivity during early life (Hamad et al., 2023)
