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Vitamin B12 functions as a cofactor for two essential enzymes: methionine synthase (involved in homocysteine metabolism and DNA synthesis) and methylmalonyl-CoA mutase (crucial for fatty acid and amino acid metabolism)

Livestock that are Co-deficient show signs of loss of appetite, reduced growth, loss in weight, and eventually anemia, emaciation, and death

LOW VITAMIN B12 AND LIPID METABOLISM: EVIDENCE FROM PRE-CLINICAL AND CLINICAL STUDIES Increase in body mass index-standard deviation score was associated with a decrease in vitamin B12 levels

Lipo-Stat-Plus MIC with B6 and B12