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This slight increase then leads to an increase in inflammatory cytokines (TNF-alpha, IL-1 beta) in macrophages[ref] Endoplasmic Reticulum (ER) stress, protein misfolding: The endoplasmic reticulum (ER) is an organelle in cells where newly synthesized proteins are folded, lipids are synthesized, and calcium is stored

Here we include three spectrum similarity features, namely Pearson correlation, cosine similarity, and spectra angle between the predicted and the observed spectra to the Percolator rescoring step

However, just as a well-functioning metabolism is essential for sustaining life, the proper metabolic function of astrocytes is crucial for maintaining neural homeostasis

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