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Such a metabolite-protein interaction seeding and stabilizing an assembled oligomeric state is a potent mode of regulation for GS given the nature of a composite active site that is completely inactive in the monomeric state (Figure 2)

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The lyophilized peptide can be purchased for laboratory research under the standard research chemicals framework, but import, possession and use for human consumption is not authorized and may be prosecuted under the Arzneimittelgesetz (AMG) or equivalent national legislation

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Int J Mol Sci 21:7460

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The overexpression of Wnt signaling in spiral ganglion neuron (SGNs) leads to increased expression of tumor protein P53-induced glycolysis and apoptosis regulator (TIGAR) and decreased levels of ROS, thereby preventing the apoptotic efflux of cascade amplification reaction (Liu et al., 2019b)

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