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In line with the finding that chemoresistant AML cells were more reliant on oxphos, another study found that residual AML PDX cells resistant to AraC had increased mitochondrial mass, high levels of ROS, and gene signatures high in oxphos (Farge et al., 2017)
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Flood C, Gustafsson M, Pitas RE, Arnaboldi L, Walzem RL, Boren J