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Lastly, gene therapy offers other avenues in that it could be combined with other therapies such as medicinal treatment or stem cell therapy or tailored to individual genetic profiles for more effective treatment (personalized medicine)

Hepatic deiodinase activity is dispensable for the maintenance of normal circulating thyroid hormone levels in mice

The growth hormone secretagogue ipamorelin counteracts the glucocorticoid-induced decrease in bone formation of adult rats

Abbreviations AMP: Antimicrobial peptide BSH: Bile salt hydrolase CAT: Catalase C

It was rather unexpected to find the CIA pathway in a cell lacking Atm1 and its cytosolic interactor, the Tah18/Dre2 complex, as it is widely accepted that the CIA pathway depends on a sulfur-containing molecule transported from the mitochondrial matrix into the cytosol via Atm1