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Webb, S
Cristiani, J
The GSSG concentrations were obtained by subtracting the glutathione value from the glutathione + GSSG value
In addition to thiol oxidation leading to disulfide bond formation by reactive oxygen species (ROS) (Suzuki et al, 2019), KEAP1 cysteine residues undergo S-alkylation by various endogenous and/or exogenous electrophiles (Wu and Papagiannakopoulos, 2020), such as succination by fumarate (Ooi et al, 2011
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