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O'Shea et al

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You can use the information to prioritize what is likely to be important for you to look at first, but you cant eliminate anything based just on your genes

[DOI] [PubMed] [Google Scholar] 53.Zhou L., Ding L., Yin P., Lu X., Wang X., Niu J., Gao P., Xu G

Mechanistically, TMAO inhibits megalin expression via PI3K/ERK, reducing albumin uptake and promoting tubular cell dysfunction, which triggers tubulointerstitial inflammation and fibrosis (Kapetanaki et al., 2022)