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This is in part because it is difficult to discern if changes are due to normal aging, common age-related disorders, or result from disease treatments

Additionally, a decline in the expression of anti-inflammatory cytokines (IL-10 and IL-4) was observed (Makker et al., 2017

Front Oncol 12:1028600 Yu X, Mai Y, Wei Y, Yu N, Gao T, Yang J (2023) Therapeutic potential of tolerance-based peptide vaccines in autoimmune diseases

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Diagnostic performance of the Fujifilm SILVAMP TB-LAM in children with presumptive tuberculosis