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Thus, the demethylation of the IL27RA promoter by procainamide restored the activation of this gene, which is known to have an anti-inflammatory effect in several models of inflammation

[22] reported that fisetin induced apoptosis specifically in senescent human endothelial cells while sparing proliferating cells, indicating its tissue-selective senolytic potential

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Data availability The data that support the findings of this study are available on request from the corresponding author

This significantly increased the C max and AUC of ginsenosides Rb1, Re, Rg1, ferulic acid, astragaloside IV, and paeoniflorin