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Studies of chondrocyte cultures suggest that it promotes proteoglycan and type II collagen synthesis, which has driven exploration of potential utility in joint and cartilage repair models

However, B12 injections do not directly cause weight loss or significantly increase metabolism in people who already have adequate B12 levels

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Schultz RA, Swoap SJ, McDaniel LD et al (1998) Differential expression of mitochondrial DNA replication factors in mammalian tissues