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Although there was no expectation that acute loss of function would match that from chronic reduction, we still observed several splicing alterations in the mutant fibroblasts that showed the same trends as the changes produced by FUS/TLS or SMN knockdown
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2022) primarily via disruption of gut microbiome homeostasis (Singh et al
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Sulforaphane appears to be a promising compound with neuroprotective properties that may play an important role in preventing PD
